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Sep 26, 2019 · Edema (or Oedema) is the abnormal accumulation of fluid in certain tissues within the body. The accumulation of fluid may be under the skin - usually in dependent areas such as the legs (peripheral edema, or ankle edema), or it may accumulate in the lungs (pulmonary edema).The location of edema can provide the health care practitioner the first clues in regard to the underlying cause of the Better Health Channel - Home